Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
1.000 GeneticVariation UNIPROT

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
1.000 Biomarker GENOMICS_ENGLAND

Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.800 Biomarker GENOMICS_ENGLAND

Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.800 Biomarker GENOMICS_ENGLAND

Entrez Id: 8405
Gene Symbol: SPOP
SPOP
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.700 Biomarker GENOMICS_ENGLAND

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.700 Biomarker GENOMICS_ENGLAND

Entrez Id: 4601
Gene Symbol: MXI1
MXI1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.660 Biomarker CTD_human

Entrez Id: 1316
Gene Symbol: KLF6
KLF6
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.500 Biomarker CTD_human

Entrez Id: 8379
Gene Symbol: MAD1L1
MAD1L1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human

Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.390 Biomarker CTD_human Prostate cancer patients with CYP3A5*3/*3 and KLK -252A > G GG/AG genotypes had decreased OR of 0.70 with 95% CI 0.50-0.98 for high prostate-specific antigen levels at diagnosis. 18306354

2008

Entrez Id: 6541
Gene Symbol: SLC7A1
SLC7A1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.330 Biomarker CTD_human CaT1 expression correlates with tumor grade in prostate cancer. 11401523

2001

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Endothelial nitric oxide synthase gene polymorphisms and the shedding of circulating tumour cells in the blood of prostate cancer patients. 12445681

2003

Entrez Id: 9
Gene Symbol: NAT1
NAT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 Biomarker CTD_human NAT1 and NAT2 are both subject to genetic polymorphism in humans, and molecular epidemiological investigations suggest that NAT1 and/or NAT2 acetylator genotype modifies risk for prostate cancers. 12618593

2003

Entrez Id: 3489
Gene Symbol: IGFBP6
IGFBP6
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.310 Therapeutic CTD_human IGFBP-6 therefore might be involved in the direct effects of DES in androgen-independent prostate cancer. 15846301

2005

Entrez Id: 8000
Gene Symbol: PSCA
PSCA
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human PSCA in situ hybridization (ISH) was performed on the cancerous pretreatment biopsy or transurethral resection of prostate (TURP) tissue of 42 men with primarily organ-confined prostate cancer before CAA, and on their tumor tissue from radical retropubic prostatectomy after CAA with bicalutamide and goserelin acetate for 3 months prior to undergoing radical prostatectomy. 16015594

2005

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.320 Biomarker CTD_human Interleukin-1 receptor antagonist haplotype associated with prostate cancer risk. 16106254

2005

Entrez Id: 9687
Gene Symbol: GREB1
GREB1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.350 Biomarker CTD_human GREB1 is expressed in proliferating prostatic tissue and prostate cancer, is regulated by androgens, and suppression of GREB1 blocks androgen-induced growth suggesting GREB1 may be critically involved in prostate cancer proliferation. 16496412

2006

Entrez Id: 606293
Gene Symbol: KLKP1
KLKP1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.320 Biomarker CTD_human KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells. 16541416

2006

Entrez Id: 567
Gene Symbol: B2M
B2M
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.330 Biomarker CTD_human Beta-2-microglobulin is an androgen-regulated secreted protein elevated in serum of patients with advanced prostate cancer. 17404077

2007

Entrez Id: 3925
Gene Symbol: STMN1
STMN1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.360 Biomarker CTD_human Stathmin expression and phosphorylation patterns were analyzed in mouse and human PCa cell lines as well as in human PCa tissue arrays. 17455228

2007

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human GSTM1 (0/0) gene polymorphism may be linked to prostate cancer risk and early age of onset in Chinese. 18304461

2008

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 19011039

2009

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 19011039

2009

Entrez Id: 101669767
Gene Symbol: SCHLAP1
SCHLAP1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.380 Biomarker CTD_human SChLAP1 levels independently predict poor outcomes, including metastasis and prostate cancer-specific mortality. 24076601

2013

Entrez Id: 10551
Gene Symbol: AGR2
AGR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human AGR2 SV-G and SV-H are potential diagnostic biomarkers for the non-invasive detection of PCa using urine exosomes. 25237833

2014