×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Functional analysis of MSH6 mutations linked to kindreds with putative hereditary non-polyposis colorectal cancer syndrome.
12019211 2002
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Mutation spectrum in HNPCC in the Israeli population.
18389388 2008
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Polyposis and early cancer in a patient with low penetrant mutations in MSH6 and APC: hereditary colorectal cancer as a polygenic trait.
16525781 2006
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes.
24689082 2014
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Improving performance of multigene panels for genomic analysis of cancer predisposition.
26845104 2016
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Characterization of a novel founder MSH6 mutation causing Lynch syndrome in the French Canadian population.
25318681 2015
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers.
25110875 2015
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.
26483394 2016
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Population-based molecular screening for Lynch syndrome: implications for personalized medicine.
23733757 2013
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Human MSH6 deficiency is associated with impaired antibody maturation.
22250089 2012
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome.
26437257 2015
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
25186627 2015
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue.
14974087 2004
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
High frequency of exon deletions and putative founder effects in French Canadian Lynch syndrome families.
19459153 2009
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Risks of Lynch syndrome cancers for MSH6 mutation carriers.
20028993 2010
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Challenges in the identification of MSH6-associated colorectal cancer: rectal location, less typical histology, and a subset with retained mismatch repair function.
21836479 2011
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study.
26552419 2015
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal?
26485756 2015
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
Biomarker
CLINGEN
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells.
7604265 1995
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
CoDP: predicting the impact of unclassified genetic variants in MSH6 by the combination of different properties of the protein.
23621914 2013
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
DNA mismatch repair.
15952900 2005
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer.
27456091 2016
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
CausalMutation
CLINVAR
Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden.
14961575 2004
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
Biomarker
CTD_human
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614 2012
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Hereditary Nonpolyposis Colorectal Neoplasms
0.640
GeneticVariation
CLINVAR
UMD-MLH1/MSH2/MSH6 databases: description and analysis of genetic variations in French Lynch syndrome families.
23729658 2013