Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54555
Gene Symbol: DDX49
DDX49
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE These findings suggested that DDX49 may be useful as a novel biomarker of lymph node metastases and therapeutic target for lung cancer metastasis. 31749282

2020

Entrez Id: 100313781
Gene Symbol: MIR718
MIR718
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE MicroRNA‑718 serves a tumor‑suppressive role in non‑small cell lung cancer by directly targeting CCNB1. 31746372

2020

Entrez Id: 23603
Gene Symbol: CORO1C
CORO1C
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Coronin-3 (coronin-1C), a homotrimer F-actin-binding protein, has been reported to be important for metastasis in several types of cancers such as lung cancer, gastric cancer, and breast cancer. 31595425

2020

Entrez Id: 100188949
Gene Symbol: LINC00426
LINC00426
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE Bioinformatics analysis of LINC00426 expression in lung cancer and its correlation with patients' prognosis. 31691516

2020

Entrez Id: 644192
Gene Symbol: NR2F2-AS1
NR2F2-AS1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Long non-coding RNA (lncRNA) NR2F2 antisense RNA 1 (NR2F2-AS1) is an oncogenic lncRNA in lung cancer. 31432342

2020

Entrez Id: 4783
Gene Symbol: NFIL3
NFIL3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Accordingly, NFIL3 promoted lung cancer cell migration and invasion in a PrPc-dependent manner. 31477838

2020

Entrez Id: 693148
Gene Symbol: MIR563
MIR563
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE In this study, we aimed to provide clues to the function of miR-563 and its direct target in lung cancer. 31766078

2020

Entrez Id: 8535
Gene Symbol: CBX4
CBX4
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE However, the effect of CBX4 in the progression of lung cancer is not fully understood. 31724308

2020

Entrez Id: 58516
Gene Symbol: SINHCAF
SINHCAF
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE FAM60A has been found showing high levels in some cancer cells, including lung cancer (A549), and pancreatic cancer (Capan-2) cell lines. 31727367

2020

Entrez Id: 5886
Gene Symbol: RAD23A
RAD23A
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE HR23A-knockdown lung cancer cells exhibit epithelial-to-mesenchymal transition and gain stemness properties through increased Twist1 stability. 31487504

2019

Entrez Id: 693185
Gene Symbol: MIR600
MIR600
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE These data suggested that miR-600 inhibited lung cancer via down-regulating METTL3 expression, and knockdown of METTL3 might be used as a novel strategy for lung cancer therapy. 30774445

2019

Entrez Id: 4001
Gene Symbol: LMNB1
LMNB1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Thus, lamin B1 acts as a tumor suppressor in lung cancer, linking aberrant nuclear structure and epigenetic patterning with malignancy. 31015297

2019

Entrez Id: 5318
Gene Symbol: PKP2
PKP2
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Subsequently, our results demonstrated that high PKP2 expression is not associated with poor survival in different gender of lung cancer patients, and is an unfavorable and independent prognostic biomarker for LUAD patients, but not for LUSC patients. 31126818

2019

Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Our results suggest that NELL1 induces lung cancer stem‑like cell differentiation, which provides a new potential therapeutic target for cancer stem cells. 30628703

2019

Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 GeneticVariation BEFREE Moreover, the patients carrying GA and AA genotypes needed more fentanyl to control pain within 48 hours after surgery (P < .05 for all).P2RX7 gene rs1718125 polymorphism is significantly associated with postoperative pain and fentanyl consumption in patients with lung cancer. 30762755

2019

Entrez Id: 2027
Gene Symbol: ENO3
ENO3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE These findings suggest that ENO3 -based targeted therapy might be promising for patients with lung cancer harboring <i>STK11</i> mutations. 31697874

2019

Entrez Id: 10953
Gene Symbol: TOMM34
TOMM34
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE Differential Expression of TOM34, AL1A1, PADI2 and KLRBA in NNK Induced Lung Cancer in Wistar Rats and their Implications. 31544692

2019

Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Studies on clock genes may help to better understand the mechanism of lung cancer development for an improved treatment. 31014124

2019

Entrez Id: 5723
Gene Symbol: PSPH
PSPH
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Phosphoserine Phosphatase Promotes Lung Cancer Progression through the Dephosphorylation of IRS-1 and a Noncanonical L-Serine-Independent Pathway. 31446747

2019

Entrez Id: 9949
Gene Symbol: AMMECR1
AMMECR1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE The aim of this study was to characterize the role of Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis chromosomal region gene 1 (AMMECR1) in human lung cancer cell lines. 31519561

2019

Entrez Id: 4849
Gene Symbol: CNOT3
CNOT3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Taken together, our results reveal a role of CNOT3 in cisplatin resistance of lung cancer and provide a potential target for lung cancer therapy. 31177396

2019

Entrez Id: 100653365
Gene Symbol: BED
BED
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE These results indicate that Zbed3 may promote lung cancer cell proliferation through regulating PCNA expression besides regulating β-catenin expression and BED finger domain can impact on this function. 30805970

2019

Entrez Id: 102800311
Gene Symbol: TP53COR1
TP53COR1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE An evident negative association between lincRNA‑p21 and miR‑17‑5p expression was observed, and the inhibitory effect of overexpressed lincRNA‑p21 on lung cancer cells was counteracted by miR‑17‑5p. 30535441

2019

Entrez Id: 145978
Gene Symbol: LINC00052
LINC00052
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 Biomarker BEFREE Some studies on the biological function of long intergenic non-protein-coding RNA 52 (LINC00052) in cancer indicate that this gene can act as either oncogene or tumor suppressor in some kinds of cancers, such as breast cancer, gastric cancer, liver cancer, and lung cancer. 31104316

2019

Entrez Id: 10653
Gene Symbol: SPINT2
SPINT2
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression BEFREE Hepatocyte growth factor activator inhibitor-2 (HAI-2) was identified to be downregulated following lung cancer progression, which was related to poor survival and tumour invasion. 30765871

2019