Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB
CUI: C0004096
Disease: Asthma
Asthma
0.500 GeneticVariation BEFREE Stronger effect sizes were observed between GWAS SNPs and gene expression in placentas than what has been reported in other tissues, such as the correlation between asthma risk allele, rs7216389-T and Gasdermin-B (GSDMB) in placenta (r2=27%) versus lung (r2=6%). 28854703

2017

Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB
CUI: C0004096
Disease: Asthma
Asthma
0.500 GeneticVariation BEFREE Two coding variants (rs2305480 and rs11078928) of the gasdermin B (GSDMB) gene in the 17q21 locus were associated with lower asthma risk in both GERA (odds ratio, 0.92; P = 1.01 × 10<sup>-6</sup>) and EVE (odds ratio, 0.85; joint P<sub>EVE</sub> = 1.31 × 10<sup>-13</sup>). 29330013

2018