Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.500 AlteredExpression BEFREE Bone loss in these patients may be due to deficient ER-alpha protein expression. 10773580

2000
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.500 Biomarker BEFREE These results demonstrate that the prevention from the ovariectomy-induced bone loss by estrogen is mediated by ER pathways and that the maintenance of BMD before ovariectomy might be compensated by other mechanisms distinct from ERalpha and ERbeta pathways. 10806217

2000
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.500 Biomarker BEFREE The estrogen receptor (ER) mixed agonists tamoxifen and raloxifene have been shown to protect against bone loss in ovariectomized rats. 9275080

1997
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.500 Biomarker HPO