Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 GeneticVariation BEFREE We investigated the influence of bacterial virulence factors and host IL-1 polymorphisms on the development of histologic abnormalities in 210 Helicobacter pylori-infected patients with chronic gastritis. cagA(+)/vacAs1(+) H. pylori strains were associated with intestinal metaplasia (IM), atrophic gastritis (AG), and severe inflammation. 12854083

2003

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker BEFREE These data suggest that TNF-alpha and IL-1 may play a direct role in Helicobacter pylori-induced hypergastrinemia. 11705745

2001

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker BEFREE Our previous study revealed that a polymorphism of the interleukin (IL) 1B gene, encoding the pro-inflammatory cytokine IL-1 beta, influenced the prevalence of persistent Helicobacter pylori (HP) infection. 11376556

2001

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker BEFREE Relation between interleukin-1beta messenger RNA in gastric fundic mucosa and gastric juice pH in patients infected with Helicobacter pylori. 10616759

1999