Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.100 Biomarker LHGDN Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins. 18490929

2008
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.100 Biomarker BEFREE Recently, leptin resistance has been nominated as a possible marker for the onset of metabolic disorders in Asian countries. 16622580

2006
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.100 Biomarker BEFREE Thus, the long-term beneficial effects of central leptin gene therapy may herald the development of newer therapeutic strategies to control the epidemic of obesity and related metabolic disorders. 12582458

2002
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.100 Biomarker BEFREE These potent and diverse effects have stimulated interest in exploring a role for leptin in the treatment of human metabolic disorders. 11469718

2001
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.100 Biomarker BEFREE The understanding of the putative direct leptin signaling pathway in skeletal muscle could be an important step towards the utilization of leptin or a leptin receptor agonist as therapeutic tools to treat obesity and its related metabolic disorders. 11145919

2001