Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.400 Biomarker BEFREE Future studies will evaluate the therapeutic efficacy of targeting the IL-17/IL-22 pathway in pulmonary inflammation. 24942687

2014
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.400 Biomarker BEFREE A cell-permeable decoy peptide based on the CC' loop sequence inhibited IL-17- or IL-25-mediated signaling in vitro, as well as IL-17- and IL-25-induced pulmonary inflammation in mice. 22045852

2011
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.400 Biomarker BEFREE Therefore preventing IL-17 function in CF may prove an important strategy in decreasing lung inflammation due to both direct and indirect effects. 19931506

2010
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.400 GeneticVariation BEFREE Importantly, Act1 deficiency in epithelial cells reduced the phenotype of allergic pulmonary inflammation due to loss of IL-17-induced neutrophilia and IL-25-induced eosinophilia, respectively. 19155512

2009
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.400 Biomarker BEFREE This review will go over experimental evidence supporting a role for the IL- 23/IL-17 axis in CF lung inflammation. 17607545

2007