Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE One of our E-GBM patients with initial gross total resection quickly recurred within 4 months, required a second resection, and then was placed on vemurafenib; she remains tumor free 21 months after second resection without neuroimaging evidence of residual disease, adding to the growing number of reports of successful treatment of BRAF-mutated glial tumors with drug. 25581727

2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE The growth inhibitory effects of UAI-201 correlated with the BRAF-V600E genotype of the glioma cell lines. 24721513

2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE We report a new IDH1 mutation associated with BRAF mutation in a very unusual glial tumor. 24857351

2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE BRAF alterations are key in certain low-grade gliomas and pediatric gliomas but rarely in high-grade gliomas in adults. 28271343

2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE The purpose of this study was to clarify the incidence of B-RAF mutations and their possible relation with tumor progression in a series of 82 human gliomas, including 49 astrocytic and 33 oligodendroglial tumors. 15791479

2005
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE The BRAF mutation V600E is critical to the pathogenesis of 10-20% of pediatric gliomas, and a small proportion of adult HGGs. 26384810

2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE Our data indicate that BRAF(V600E) is a common genetic alteration in low-grade glial tumors with neuronal component or differentiation. 25346165

2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 GeneticVariation BEFREE CDKN2A, and PTEN in high-grade gliomas, followed by BRAF fusions in low-grade gliomas and H3F3A mutations in pediatric gliomas. 26681766

2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0017638
Disease: Glioma
Glioma 		0.600 CausalMutation CGI