Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1183
Gene Symbol: CLCN4
CLCN4
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.100 Biomarker HPO

Entrez Id: 6609
Gene Symbol: SMPD1
SMPD1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.100 Biomarker HPO

Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.100 Biomarker HPO

Entrez Id: 64072
Gene Symbol: CDH23
CDH23
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.100 Biomarker HPO

Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.400 Biomarker PSYGENET   There is an association between specific symptoms of bipolar disorder and the P2RX7 gene. 22017219

2012

Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.010 Biomarker BEFREE <b>Results:</b> Pearson correlation analysis showed that serum lithium concentrations were positively correlated with creatinine concentrations (r=0.147, <i>P</i>=0.046), Mg<sup>2+</sup> concentrations (r=0.151, <i>P</i>=0.04), and the percentage of neutrophils (r=0.178, <i>P</i>=0.015) and negatively correlated with high-density lipoprotein (HDL) concentrations (r=-0.142, <i>P</i>=0.05), apolipoprotein A1 concentrations (r=-0.169, <i>P</i>=0.02), and Na<sup>+</sup> concentrations (r=-0.148, <i>P</i>=0.046) in 186 patients with BD. 31371966

2019

Entrez Id: 2539
Gene Symbol: G6PD
G6PD
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 GeneticVariation BEFREE (c) Reported linkages of bipolar illness to colorblind and G6PD loci are compatible with known map distances between X-chromosome loci. 6454708

1981

Entrez Id: 10922
Gene Symbol: FASTK
FASTK
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.020 Biomarker BEFREE 1) There were no differences between BD-P and BD-NP in the GAF-F score or in the FAST total score. 29316520

2018

Entrez Id: 3628
Gene Symbol: INPP1
INPP1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 GeneticVariation BEFREE Manic-depressive illness: an association study with the inositol polyphosphate 1-phosphatase and serotonin transporter genes. 11901356

2002

Entrez Id: 958
Gene Symbol: CD40
CD40
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.070 Biomarker BEFREE Bipolar disorder was significantly associated with smaller P300 amplitude and decreased P50 suppression. 17224092

2007

Entrez Id: 8874
Gene Symbol: ARHGEF7
ARHGEF7
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.070 Biomarker BEFREE Bipolar disorder was significantly associated with smaller P300 amplitude and decreased P50 suppression. 17224092

2007

Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.070 Biomarker BEFREE Bipolar disorder was significantly associated with smaller P300 amplitude and decreased P50 suppression. 17224092

2007

Entrez Id: 115482723
Gene Symbol: H3P40
H3P40
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.070 Biomarker BEFREE Bipolar disorder was significantly associated with smaller P300 amplitude and decreased P50 suppression. 17224092

2007

Entrez Id: 51008
Gene Symbol: ASCC1
ASCC1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.070 Biomarker BEFREE Bipolar disorder was significantly associated with smaller P300 amplitude and decreased P50 suppression. 17224092

2007

Entrez Id: 2158
Gene Symbol: F9
F9
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 Biomarker PSYGENET Manic depressive illness not linked to factor IX region in an independent series of pedigrees. 1980485

1990

Entrez Id: 2158
Gene Symbol: F9
F9
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 Biomarker BEFREE Manic depressive illness not linked to factor IX region in an independent series of pedigrees. 1980485

1990

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 GeneticVariation BEFREE Bipolar disorder and polymorphisms of glutathione S-transferases M1 (GSTM1) and T1 (GSTT1). 20674986

2011

Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 GeneticVariation BEFREE Bipolar disorder and polymorphisms of glutathione S-transferases M1 (GSTM1) and T1 (GSTT1). 20674986

2011

Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.420 GeneticVariation GWASDB Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸). 22205951

2011

Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.420 GeneticVariation GWASCAT Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸). 22205951

2011

Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.420 Biomarker PSYGENET Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸). 22205951

2011

Entrez Id: 152330
Gene Symbol: CNTN4
CNTN4
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.300 Biomarker PSYGENET Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6). 22205951

2011

Entrez Id: 27255
Gene Symbol: CNTN6
CNTN6
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker PSYGENET Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6). 22205951

2011

Entrez Id: 85358
Gene Symbol: SHANK3
SHANK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.050 GeneticVariation BEFREE Bipolar affective disorder and early dementia onset in a male patient with SHANK3 deletion. 22922660

2012

Entrez Id: 706
Gene Symbol: TSPO
TSPO
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 GeneticVariation BEFREE Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO). 23942012

2013