Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C3241937
Disease: Nonalcoholic Steatohepatitis
Nonalcoholic Steatohepatitis 		0.310 Biomarker CTD_human Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease. 21664615

2011
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0221056
Disease: Adult type dermatomyositis
Adult type dermatomyositis 		0.310 Biomarker CTD_human Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis. 19035492

2008
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0263666
Disease: Dermatomyositis, Childhood Type
Dermatomyositis, Childhood Type 		0.310 Biomarker CTD_human TNFalpha and IL-1 genetic polymorphisms contribute to the development of juvenile DM and may also be indicators of disease severity. 19035492

2008
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0011991
Disease: Diarrhea
Diarrhea 		0.310 Biomarker CTD_human Induction of nitric oxide synthase in rat intestine by interleukin-1alpha may explain diarrhea associated with zinc deficiency. 9278552

1997
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0085655
Disease: Polymyositis
Polymyositis 		0.310 Biomarker CTD_human Cytokine expression in the muscle of HIV-infected patients: evidence for interleukin-1 alpha accumulation in mitochondria of AZT fibers. 7979221

1994
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma. 27738319

2016
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.300 Biomarker CTD_human Involvement of the HIF-1α and Wnt/β-catenin pathways in the protective effects of losartan on fatty liver graft with ischaemia/reperfusion injury. 23875703

2014
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0002631
Disease: Infection of amniotic cavity
Infection of amniotic cavity 		0.300 Biomarker CTD_human Interleukin-1 in lipopolysaccharide induced chorioamnionitis in the fetal sheep. 21493953

2011
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0021368
Disease: Inflammation
Inflammation 		0.300 Biomarker CTD_human Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats. 21467745

2011
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0021368
Disease: Inflammation
Inflammation 		0.300 Biomarker CTD_human This study provides compelling evidence that IL-1α is central to the initiation of smoke-induced neutrophilic inflammation and suggests that IL-1α/IL-1R1 targeted therapies may be relevant for limiting inflammation and exacerbations in COPD. 22163019

2011
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C1275592
Disease: Funisitis (disorder)
Funisitis (disorder) 		0.300 Biomarker CTD_human Interleukin-1 in lipopolysaccharide induced chorioamnionitis in the fetal sheep. 21493953

2011
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0274861
Disease: Arsenic Poisoning, Inorganic
Arsenic Poisoning, Inorganic 		0.300 Biomarker CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338

2006
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0274862
Disease: Nervous System, Organic Arsenic Poisoning
Nervous System, Organic Arsenic Poisoning 		0.300 Biomarker CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338

2006
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0311375
Disease: Arsenic Poisoning
Arsenic Poisoning 		0.300 Biomarker CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338

2006
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0751851
Disease: Arsenic Encephalopathy
Arsenic Encephalopathy 		0.300 Biomarker CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338

2006
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0751852
Disease: Arsenic Induced Polyneuropathy
Arsenic Induced Polyneuropathy 		0.300 Biomarker CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338

2006
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.300 Biomarker CTD_human Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914

2005
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0917798
Disease: Cerebral Ischemia
Cerebral Ischemia 		0.300 Biomarker CTD_human Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914

2005
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0019061
Disease: Hemolytic-Uremic Syndrome
Hemolytic-Uremic Syndrome 		0.300 Biomarker CTD_human The role of circulating immune complexes and biocompatibility of staphylococcal protein A immunoadsorption in mitomycin C-induced hemolytic uremic syndrome. 15384034

2004
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0020649
Disease: Hypotension
Hypotension 		0.300 Biomarker CTD_human The role of circulating immune complexes and biocompatibility of staphylococcal protein A immunoadsorption in mitomycin C-induced hemolytic uremic syndrome. 15384034

2004
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0206637
Disease: Mesenchymal Chondrosarcoma
Mesenchymal Chondrosarcoma 		0.300 Biomarker CTD_human Mesenchymal chondrosarcoma: molecular characterization by a proteomic approach, with morphogenic and therapeutic implications. 12817616

2003
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Biomarker CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271

2003
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0751211
Disease: Hyperalgesia, Primary
Hyperalgesia, Primary 		0.300 Biomarker CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271

2003
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary 		0.300 Biomarker CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271

2003
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0751213
Disease: Tactile Allodynia
Tactile Allodynia 		0.300 Biomarker CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271

2003