Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54790
Gene Symbol: TET2
TET2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.350 Biomarker CTD_human Among men carrying two A alleles at rs7679673 in TET2, the risk of prostate cancer associated with high aldrin use was 3.67 times those with no use (95% CI: 1.43, 9.41) (P-interaction= 0.006). 23593118

2013

Entrez Id: 23301
Gene Symbol: EHBP1
EHBP1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.420 Biomarker CTD_human Among men carrying two T alleles at rs2710647 in EH domain binding protein 1 (EHBP1) SNP, the risk of prostate cancer in those with high malathion use was 3.43 times those with no use (95% CI: 1.44-8.15) (P-interaction= 0.003). 23593118

2013

Entrez Id: 2938
Gene Symbol: GSTA1
GSTA1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.330 Biomarker CTD_human Among smokers, the frequency of the GSTA1*A/*B or *B/*B genotype in patients with prostate cancer (27.8%) showed a statistically significant increase compared with the control group frequency (18.2%; odds ratio [OR] =1.72; 95% CI, 1.01-2.94). 15616829

2005

Entrez Id: 3817
Gene Symbol: KLK2
KLK2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Among the SNPs studied, the A allele of the KLK2-SNP1 (G>A, rs2664155) and the T allele of the KLK2-SNP5 (C>T, rs198977) polymorphisms showed positive associations with prostate cancer, adjusted ORs for KLK2-SNP1 AG and AA genotypes being 1.4 [95% confidence interval (95% CI), 1.2-1.8; P=0.002] and for KLK2-SNP5 TT or CT genotypes being 1.3 (95% CI, 1.1-1.6; P=0.05). 17085659

2006

Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.300 Biomarker CTD_human Amphiphilic dimers and monomers and hydrophilic dimers of AChE were identified in BHP and PC tissues. 20356562

2010

Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.310 Biomarker CTD_human An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. 27783944

2016

Entrez Id: 2115
Gene Symbol: ETV1
ETV1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. 27783944

2016

Entrez Id: 2118
Gene Symbol: ETV4
ETV4
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. 27783944

2016

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. 27783944

2016

Entrez Id: 2119
Gene Symbol: ETV5
ETV5
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.390 Biomarker CTD_human An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. 27783944

2016

Entrez Id: 354
Gene Symbol: KLK3
KLK3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.500 Biomarker CTD_human An open-label phase II study of low-dose thalidomide in androgen-independent prostate cancer. 12644816

2003

Entrez Id: 2247
Gene Symbol: FGF2
FGF2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human An open-label phase II study of low-dose thalidomide in androgen-independent prostate cancer. 12644816

2003

Entrez Id: 4292
Gene Symbol: MLH1
MLH1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Analysis of candidate genes for prostate cancer. 15583422

2004

Entrez Id: 3249
Gene Symbol: HPN
HPN
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Analysis of candidate genes for prostate cancer. 15583422

2004

Entrez Id: 2014
Gene Symbol: EMP3
EMP3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.300 Biomarker CTD_human Analysis of candidate genes for prostate cancer. 15583422

2004

Entrez Id: 858
Gene Symbol: CAV2
CAV2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.300 Biomarker CTD_human Analysis of candidate genes for prostate cancer. 15583422

2004

Entrez Id: 8537
Gene Symbol: BCAS1
BCAS1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.300 Biomarker CTD_human Analysis of candidate genes for prostate cancer. 15583422

2004

Entrez Id: 5567
Gene Symbol: PRKACB
PRKACB
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.300 Biomarker CTD_human Androgen dependent regulation of protein kinase A subunits in prostate cancer cells. 16949795

2007

Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.340 Biomarker CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
1.000 Therapeutic CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
1.000 Biomarker CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 354
Gene Symbol: KLK3
KLK3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.500 Biomarker CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation. 23704919

2013

Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Androgen receptors in prostate cancer. 12237244

2002