rs495139
|
|
Ovarian Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In expression quantitative trait locus (eQTL) analysis, the rs495139 allele was positively associated with ENOSF1 mRNA expression in normal tissues of the gastrointestinal system, particularly esophageal mucosa (<i>r</i> = 0.51, <i>p</i> = 1.7 × 10<sup>-28</sup>), and nonsignificantly in five MOC tumors.
|
30134598 |
2018 |
rs495139
|
|
Ovarian Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Biomarkers that distinguish ovarian carcinoma types are few, and TYMS rs495139 may provide a novel clue to type etiology.
|
20570913 |
2010 |
rs1271572
|
|
Ovarian Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium.
|
21673961 |
2011 |
rs1271572
|
|
Ovarian Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Compared to homozygous common allele carriers, homozygous carriers of variant alleles for rs1271572 [odds ratio (OR) = 1.79, 95% confidence interval (CI):1.15-2.79, p global = 0.01] and rs1256030 [OR = 1.67, CI: 1.08-2.59, p global = 0.04], and women with haplotypes, including variant alleles of rs1271572, rs1256030, and rs1256031 SNPs [OR = 1.75, CI: 1.17-2.63, p global = 0.007], had significantly increased risk of ovarian carcinoma.
|
18704709 |
2009 |
rs9110
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we determined the distribution of LTF gene polymorphisms (rs1126477, rs1126478, rs2073495, and rs9110) in the Chinese Han population and investigated whether these polymorphisms were associated with increased risk of ovarian carcinoma in the Chinese.
|
21937479 |
2011 |
rs861539
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The obtained results indicate that XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be positively associated with the incidence of ovarian carcinoma in the population of Polish women.
|
26801223 |
2016 |
rs80358721
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Three ovarian cancer cell lines (PEO1, PEO4, and PEO6) were derived from a BRCA2 mutation [5193C>G (Y1655X)] carrier with ovarian carcinoma with acquired cisplatin resistance and a secondary BRCA2 mutation [5193C>T (Y1655Y)] that canceled the inherited mutation.
|
19654294 |
2009 |
rs5275
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association of PTGS2 rs5275 with nonserous ovarian carcinoma and possible effect modification by NSAID use needs further validation, preferably in prospective studies.
|
20559705 |
2010 |
rs3218536
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The obtained results indicate that XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be positively associated with the incidence of ovarian carcinoma in the population of Polish women.
|
26801223 |
2016 |
rs25487
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Impact of RAD51 G135C and XRCC1 Arg399Gln polymorphisms on ovarian carcinoma risk in Serbian women.
|
26406958 |
2015 |
rs238406
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The R156R (C to A, rs238406) polymorphism of ERCC2 gene was investigated by the PCR-RFLP technique in 400 patients with ovarian carcinoma and 400 age- and sex matched non-cancer controls.
|
27888704 |
2017 |
rs2073495
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we determined the distribution of LTF gene polymorphisms (rs1126477, rs1126478, rs2073495, and rs9110) in the Chinese Han population and investigated whether these polymorphisms were associated with increased risk of ovarian carcinoma in the Chinese.
|
21937479 |
2011 |
rs1799950
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Further characterisation of rs1799950 is now warranted in relation to chemosensitivity and susceptibility to developing ovarian carcinoma.
|
29298688 |
2018 |
rs1256031
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Compared to homozygous common allele carriers, homozygous carriers of variant alleles for rs1271572 [odds ratio (OR) = 1.79, 95% confidence interval (CI):1.15-2.79, p global = 0.01] and rs1256030 [OR = 1.67, CI: 1.08-2.59, p global = 0.04], and women with haplotypes, including variant alleles of rs1271572, rs1256030, and rs1256031 SNPs [OR = 1.75, CI: 1.17-2.63, p global = 0.007], had significantly increased risk of ovarian carcinoma.
|
18704709 |
2009 |
rs1256030
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Compared to homozygous common allele carriers, homozygous carriers of variant alleles for rs1271572 [odds ratio (OR) = 1.79, 95% confidence interval (CI):1.15-2.79, p global = 0.01] and rs1256030 [OR = 1.67, CI: 1.08-2.59, p global = 0.04], and women with haplotypes, including variant alleles of rs1271572, rs1256030, and rs1256031 SNPs [OR = 1.75, CI: 1.17-2.63, p global = 0.007], had significantly increased risk of ovarian carcinoma.
|
18704709 |
2009 |
rs121913377
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Germ line and somatic mutations of BRAF V599E in ovarian carcinoma.
|
17309670 |
2007 |
rs121434596
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
NRAS mutation in codon 13 (G13D, p.Gly13Asp; nucleotide: c.38G>A) was found in one patient, a woman with low-grade serous ovarian carcinoma.
|
29682098 |
2018 |
rs113488022
|
|
Ovarian Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Germ line and somatic mutations of BRAF V599E in ovarian carcinoma.
|
17309670 |
2007 |