|
rs779221554
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs770462360
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs757496714
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs375412266
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs371854396
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs17855787
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs1567176006
|
|
Glioblastoma Multiforme
|
G |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs1558650888
|
|
Glioblastoma Multiforme
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs1466858740
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs1402272180
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs1384093596
|
|
Glioblastoma Multiforme
|
|
0.700 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs371409680
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
Functional analysis of the p53 alleles present in the patient's tumor indicated that the germ-line p53(R283H) could transactivate the CDKN1A((p21, WAF1, cip1, SDI1)) but not the BAX gene and retained the ability to induce growth arrest of human glioblastoma cells.
|
12019170 |
2002 |
|
rs121909218
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results were also confirmed by expressions of Ad-wt-PTEN and Ad-G129E-PTEN in other glioblastoma cells lacking functional PTEN, U251MG, and U373MG.
|
12414663 |
2002 |
|
rs74315452
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
Activation of caspase-1 and caspase-3 is observed also in neuroblastoma lines expressing other fALS-SOD1s (G37R, G85R, and I113T) cocultured with glioblastoma lines expressing the corresponding mutant enzymes.
|
15208263 |
2004 |
|
rs373584770
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
Activation of caspase-1 and caspase-3 is observed also in neuroblastoma lines expressing other fALS-SOD1s (G37R, G85R, and I113T) cocultured with glioblastoma lines expressing the corresponding mutant enzymes.
|
15208263 |
2004 |
|
rs121912438
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
Furthermore, selective death of embryonal spinal motor neurons from G93A-SOD1 transgenic mice is induced by coculture with G93A-glioblastoma and prevented by inhibition of NO synthase.
|
15208263 |
2004 |
|
rs1045642
|
|
Glioblastoma Multiforme
|
|
0.020 |
GeneticVariation
|
BEFREE |
Although the C3435T polymorphism does not appear to be associated with other types of glioma, we cannot rule out that this MDR1 polymorphism may be associated with glioblastoma among men.
|
15947495 |
2005 |
|
rs1801275
|
|
Glioblastoma Multiforme
|
|
0.030 |
GeneticVariation
|
BEFREE |
In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96).
|
16024651 |
2005 |
|
rs1805015
|
|
Glioblastoma Multiforme
|
|
0.020 |
GeneticVariation
|
BEFREE |
In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96).
|
16024651 |
2005 |
|
rs1259560536
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96).
|
16024651 |
2005 |
|
rs2017309
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
A genetic polymorphism of the CHEK2 gene (CHEK2 SNP rs2017309 A/T) was genotyped in a series of glioblastoma patients (n = 213) and population controls (n = 192).
|
17016233 |
2006 |
|
rs1217691063
|
|
Glioblastoma Multiforme
|
|
0.020 |
GeneticVariation
|
BEFREE |
We investigated MTR c.2756A>G, MTHFR c.677C>T, and a third polymorphism, transcobalamin 2 c.776C>G (P259R), for a potential association with the formation of glioblastoma multiforme.
|
17119065 |
2006 |
|
rs1805087
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated MTR c.2756A>G, MTHFR c.677C>T, and a third polymorphism, transcobalamin 2 c.776C>G (P259R), for a potential association with the formation of glioblastoma multiforme.
|
17119065 |
2006 |
|
rs1801198
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated MTR c.2756A>G, MTHFR c.677C>T, and a third polymorphism, transcobalamin 2 c.776C>G (P259R), for a potential association with the formation of glioblastoma multiforme.
|
17119065 |
2006 |
|
rs3092993
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
Six hundred and eighty glioma cases (298 glioblastoma (GBM)), 503 meningioma cases, and 1555 controls recruited in the Nordic-UK Interphone study, were analysed in association with three polymorphisms in p53 (rs2287499, rs1042533, rs1625895) and five polymorphisms in ATM ( rs228599, rs3092992, rs664143, rs170548, rs3092993).
|
17151932 |
2007 |