|
rs75932628
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
A rare missense mutation (rs75932628-T) in the gene encoding the triggering receptor expressed on myeloid cells 2 (TREM2), which was predicted to result in an R47H substitution, was found to confer a significant risk of Alzheimer's disease in Iceland (odds ratio, 2.92; 95% confidence interval [CI], 2.09 to 4.09; P=3.42×10(-10)).
|
23150908 |
2013 |
|
rs744373
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs744373
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
|
21460840 |
2011 |
|
rs744373
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
|
21627779 |
2011 |
|
rs744373
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
|
21390209 |
2011 |
|
rs6656401
|
|
Alzheimer's Disease
|
A |
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
|
24162737 |
2013 |
|
rs6656401
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs6656401
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
|
22005930 |
2012 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
|
20885792 |
2010 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
|
19136949 |
2009 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study of Alzheimer's disease.
|
22832961 |
2012 |
|
rs405509
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
|
21379329 |
2011 |
|
rs405509
|
|
Alzheimer's Disease
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
|
24755620 |
2014 |
|
rs3865444
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs3851179
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs3851179
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
These associations were replicated in stage 2 (2,023 cases and 2,340 controls), producing compelling evidence for association with Alzheimer's disease in the combined dataset (rs11136000, P = 8.5 x 10(-10), odds ratio = 0.86; rs3851179, P = 1.3 x 10(-9), odds ratio = 0.86).
|
19734902 |
2009 |
|
rs3764650
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
|
21460840 |
2011 |
|
rs2373115
|
|
Alzheimer's Disease
|
G |
0.900 |
GeneticVariation
|
GWASDB |
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
|
17553421 |
2007 |
|
rs2373115
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs2075650
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of age-at-onset in Alzheimer's disease.
|
22005931 |
2012 |
|
rs2075650
|
|
Alzheimer's Disease
|
G |
0.900 |
GeneticVariation
|
GWASDB |
Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
|
24755620 |
2014 |
|
rs2075650
|
|
Alzheimer's Disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |