Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		G 0.800 CausalMutation CLINVAR RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. 20179705

2010
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		A 0.800 CausalMutation CLINVAR RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. 20130576

2010
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		C 0.800 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		A 0.800 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		A 0.800 CausalMutation CLINVAR Distinct sets of genetic alterations in melanoma. 16291983

2005
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		G 0.800 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.800 GeneticVariation BEFREE We present the clinical course, unique morphology, angiogenic properties, growth characteristics using in vivo experiments and 3D cell culture, and results of the exome gene sequencing of an intensively pigmented melanogenic cell line MUG-Mel2, derived from a cutaneous metastasis of an aggressive NRAS p. Q61R mutated melanoma. 28522871

2017