Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.320 None 1.000 2 0 1999 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.340 None 0.500 2 0 2009 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.330 None 0.750 4 0 2005 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 95 0.281 0.923 5.9E-03 0.330 None 0.667 3 0 2008 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.300 None 1.000 1 0 2007 2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.330 None 1.000 3 0 2007 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 35 0.324 0.923 4.3E-02 0.300 None 1.000 1 0 2001 2001
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.320 None 1.000 3 0 2005 2013
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 98 0.333 0.923 0.84 0.300 None 1.000 1 0 2007 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.360 None 1.000 5 0 2001 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 115 0.338 0.962 1.9E-03 0.340 None 0.750 4 0 2002 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.400 None 0.400 5 0 2004 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 114 0.349 0.846 0.46 0.330 None 1.000 1 0 2015 2019
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 63 0.351 0.846 0.99 0.310 None 1.000 2 0 2011 2014
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 241 0.356 0.846 1.2E-04 0.400 None 0.800 5 0 1989 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 45 0.357 0.923 8.5E-17 0.300 None 0.500 2 0 2009 2010
Entrez Id: 847
Gene Symbol: CAT
CAT 		P04040 catalase Enzyme 171 0.359 0.962 1.6E-10 0.320 None 1.000 2 0 1995 2015
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 44 0.368 0.923 0.82 0.320 None 1.000 1 0 2013 2018
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 53 0.370 0.923 2.4E-07 0.300 None 1.000 2 0 1991 2010
Entrez Id: 2688
Gene Symbol: GH1
GH1 		P01241 growth hormone 1 Signaling 32 0.373 0.923 3.0E-02 0.330 None 1.000 5 0 1991 2010
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.330 None 1.000 2 0 2000 2019
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		P19838 nuclear factor kappa B subunit 1 Transcription factor 33 0.396 0.923 1.00 0.350 None 1.000 4 0 2007 2018
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 45 0.396 0.846 3.2E-06 0.310 None 1.000 1 0 2011 2017
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 82 0.400 0.923 1.1E-06 0.400 None 0.875 1 0 1999 2018
Entrez Id: 7450
Gene Symbol: VWF
VWF 		P04275 von Willebrand factor Enzyme modulator 36 0.408 0.885 3.2E-25 0.300 None 1.000 1 0 2013 2013