Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.700 None 0.979 721 18 2006 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS
P35637 FUS RNA binding protein Nucleic acid binding 301 0.470 0.846 1.00 0.700 None 0.981 310 16 2009 2020
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS
P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.100 None 0.966 145 9 1994 2020
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
Q99700 ataxin 2 Nucleic acid binding 341 0.482 0.808 0.85 0.700 None 0.971 68 4 2006 2019
Entrez Id: 10133
Gene Symbol: OPTN
OPTN
Q96CV9 optineurin 136 0.548 0.808 5.9E-18 0.700 None 0.954 65 8 2010 2020
Entrez Id: 7415
Gene Symbol: VCP
VCP
P55072 valosin containing protein 376 0.469 0.923 1.00 0.500 None 0.962 52 8 2008 2020
Entrez Id: 283
Gene Symbol: ANG
ANG
P03950 angiogenin 185 0.511 0.769 0.29 0.500 None 0.959 49 7 2004 2019
Entrez Id: 29978
Gene Symbol: UBQLN2
UBQLN2
Q9UHD9 ubiquilin 2 59 0.656 0.462 0.85 0.500 None 0.980 49 9 2011 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.918 49 2 2003 2018
Entrez Id: 6506
Gene Symbol: SLC1A2
SLC1A2
P43004 solute carrier family 1 member 2 Transporter 208 0.511 0.731 0.71 0.400 None 0.921 38 4 1996 2019
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.700 None 0.974 38 4 2009 2020
Entrez Id: 5216
Gene Symbol: PFN1
PFN1
P07737 profilin 1 119 0.565 0.769 0.73 0.500 None 1.000 36 5 2012 2019
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
P07196 neurofilament light 247 0.488 0.769 0.100 None 0.968 31 0 1990 2020
Entrez Id: 9217
Gene Symbol: VAPB
VAPB
O95292 VAMP associated protein B and C Transporter 55 0.666 0.423 0.58 0.500 None 0.967 30 3 2004 2019
Entrez Id: 57679
Gene Symbol: ALS2
ALS2
Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 84 0.647 0.423 8.7E-12 0.200 None 1.000 25 0 2001 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 0.920 25 2 2000 2020
Entrez Id: 6606
Gene Symbol: SMN1
SMN1
Q16637 survival of motor neuron 1, telomeric Epigenetic regulator 317 0.454 0.769 1.6E-02 0.100 None 0.917 24 0 1996 2018
Entrez Id: 6607
Gene Symbol: SMN2
SMN2
Q16637 survival of motor neuron 2, centromeric 299 0.459 0.769 0.10 0.100 None 0.870 23 0 1996 2018
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.100 None 1.000 22 1 1999 2018
Entrez Id: 2896
Gene Symbol: GRN
GRN
P28799 granulin precursor 412 0.435 0.846 7.0E-02 0.100 None 0.955 22 5 2007 2018
Entrez Id: 400916
Gene Symbol: CHCHD10
CHCHD10
Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 112 0.623 0.462 5.4E-06 0.500 None 0.955 22 3 2014 2020
Entrez Id: 23524
Gene Symbol: SRRM2
SRRM2
Q9UQ35 serine/arginine repetitive matrix 2 101 0.564 0.692 1.00 0.100 None 1.000 21 1 2009 2019
Entrez Id: 27303
Gene Symbol: RBMS3
RBMS3
Q6XE24 RNA binding motif single stranded interacting protein 3 116 0.553 0.692 0.21 0.100 None 1.000 21 2 2009 2019
Entrez Id: 56902
Gene Symbol: PNO1
PNO1
Q9NRX1 partner of NOB1 homolog 99 0.564 0.615 0.23 0.100 None 1.000 21 0 2009 2019
Entrez Id: 5725
Gene Symbol: PTBP1
PTBP1
P26599 polypyrimidine tract binding protein 1 172 0.517 0.769 1.00 0.100 None 1.000 21 2 2009 2019