Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.470 None 0.857 0 3 2001 2009
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.400 None 0.971 0 2 2003 2019
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ
Q12913 protein tyrosine phosphatase receptor type J Enzyme 8 0.606 0.615 1.3E-11 0.350 None 1.000 0 2 2002 2010
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 56 0.362 0.769 1.00 0.330 None 1.000 0 0 2001 2019
Entrez Id: 25788
Gene Symbol: RAD54B
RAD54B
O95073 Q9Y620 RAD54 homolog B 13 0.659 0.462 8.1E-13 0.320 None 1.000 0 1 1999 2002
Entrez Id: 5606
Gene Symbol: MAP2K3
MAP2K3
P46734 mitogen-activated protein kinase kinase 3 Kinase 1 0.619 0.615 2.2E-02 0.300 None 0 2
Entrez Id: 894
Gene Symbol: CCND2
CCND2
P30279 cyclin D2 Enzyme modulator 42 0.477 0.808 0.99 0.610 None 1.000 1 3 2004 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.600 None 1.000 1 2 1998 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.600 None 0.964 1 0 1995 2019
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A
O00220 TNF receptor superfamily member 10a 29 0.521 0.731 5.1E-15 0.520 None 1.000 1 0 2006 2019
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12
Q05209 protein tyrosine phosphatase non-receptor type 12 2 0.641 0.769 1.00 0.510 None 1.000 1 1 1994 2018
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 71 0.413 0.846 0.13 0.500 None 1.000 1 0 1995 2017
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.500 None 0.990 1 10 1988 2020
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 19 0.521 0.769 1.3E-18 0.500 None 1.000 1 1 2005 2018
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 29 0.485 0.846 1.00 0.480 None 1.000 1 2 2005 2019
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 20 0.507 0.692 0.57 0.470 None 1.000 1 0 2001 2018
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 Signaling 49 0.413 0.885 0.13 0.400 None 1.000 1 0 2000 2019
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
P09237 matrix metallopeptidase 7 Enzyme 10 0.446 0.885 1.0E-09 0.400 None 1.000 1 0 1994 2019
Entrez Id: 2520
Gene Symbol: GAST
GAST
P01350 gastrin 21 0.485 0.808 2.7E-03 0.400 None 0.929 1 0 1986 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.966 1 0 1996 2019
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 51 0.417 0.885 0.32 0.400 None 1.000 1 0 1997 2019
Entrez Id: 51176
Gene Symbol: LEF1
LEF1
Q9UJU2 lymphoid enhancer binding factor 1 12 0.486 0.769 1.00 0.400 None 1.000 1 0 1997 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.400 None 0.957 1 0 1999 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 114 0.349 0.846 0.46 0.400 None 1.000 1 0 2005 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 59 0.390 0.885 4.4E-02 0.400 None 0.875 1 0 1996 2017