Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.090 None 1.000 9 3 1991 2019
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.100 None 1.000 11 2 2008 2019
Entrez Id: 2741
Gene Symbol: GLRA1
GLRA1
P23415 glycine receptor alpha 1 Ion channel 75 0.628 0.500 1.6E-04 0.050 None 1.000 5 2 1994 2006
Entrez Id: 1355
Gene Symbol: COX15
COX15
Q7KZN9 cytochrome c oxidase assembly homolog COX15 70 0.638 0.538 1.1E-13 0.010 None 1.000 1 2 2016 2016
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.010 None 1.000 1 2 2019 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 1.000 27 1 2001 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.260 None 1.000 7 1 1997 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.350 None 1.000 6 1 1995 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.040 None 0.750 4 1 1998 2019
Entrez Id: 7276
Gene Symbol: TTR
TTR
P02766 transthyretin Transporter 461 0.423 0.885 0.52 0.030 None 1.000 3 1 2001 2019
Entrez Id: 1719
Gene Symbol: DHFR
DHFR
P00374 dihydrofolate reductase Enzyme 191 0.513 0.808 3.4E-02 0.310 None 1.000 2 1 2011 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.310 None 1.000 2 1 1997 2011
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.020 None 1.000 2 1 2018 2019
Entrez Id: 3798
Gene Symbol: KIF5A
KIF5A
Q12840 kinesin family member 5A Cellular structure 112 0.593 0.731 1.00 0.020 None 1.000 2 1 2018 2018
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS
P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.020 None 1.000 2 1 2017 2018
Entrez Id: 51010
Gene Symbol: EXOSC3
EXOSC3
Q9NQT5 exosome component 3 Enzyme 84 0.610 0.692 2.4E-04 0.020 None 1.000 2 1 2018 2020
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 370 0.436 0.808 3.9E-03 0.020 None 1.000 2 1 2010 2019
Entrez Id: 1917
Gene Symbol: EEF1A2
EEF1A2
Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 166 0.554 0.808 1.00 0.010 None 1.000 1 1 2015 2015
Entrez Id: 10456
Gene Symbol: HAX1
HAX1
O00165 HCLS1 associated protein X-1 59 0.631 0.577 8.5E-08 0.010 None 1.000 1 1 2007 2007
Entrez Id: 10577
Gene Symbol: NPC2
NPC2
P61916 NPC intracellular cholesterol transporter 2 81 0.612 0.769 1.8E-03 0.010 None 1.000 1 1 2013 2013
Entrez Id: 65055
Gene Symbol: REEP1
REEP1
Q9H902 receptor accessory protein 1 Transporter 79 0.653 0.423 0.99 0.010 None 1.000 1 1 2018 2018
Entrez Id: 7123
Gene Symbol: CLEC3B
CLEC3B
P05452 C-type lectin domain family 3 member B Extracellular structure 27 0.729 0.308 2.1E-03 0.010 None < 0.001 1 1 2019 2019
Entrez Id: 785
Gene Symbol: CACNB4
CACNB4
O00305 calcium voltage-gated channel auxiliary subunit beta 4 Ion channel 54 0.653 0.231 3.1E-02 0.010 None 1.000 1 1 2019 2019
Entrez Id: 79876
Gene Symbol: UBA5
UBA5
Q9GZZ9 ubiquitin like modifier activating enzyme 5 Enzyme 150 0.582 0.731 2.5E-04 0.010 None 1.000 1 1 2016 2016
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
P07858 cathepsin B Enzyme 304 0.457 0.846 5.9E-11 0.010 None 1.000 1 1 2019 2019