Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.400 None 0.969 32 8 2003 2019
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1 		P02458 collagen type II alpha 1 chain 496 0.444 0.846 1.00 0.500 None 0.941 68 5 1993 2020
Entrez Id: 4314
Gene Symbol: MMP3
MMP3 		P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.100 None 0.981 54 5 1996 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.400 None 0.997 381 4 1992 2020
Entrez Id: 8038
Gene Symbol: ADAM12
ADAM12 		O43184 ADAM metallopeptidase domain 12 Enzyme 107 0.565 0.731 5.7E-07 0.080 None 0.875 8 4 2009 2017
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1 		P12107 collagen type XI alpha 1 chain 268 0.495 0.846 1.00 0.150 None 1.000 6 4 2013 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 112 3 1990 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.500 None 1.000 50 3 2000 2020
Entrez Id: 1311
Gene Symbol: COMP
COMP 		P49747 cartilage oligomeric matrix protein 230 0.503 0.808 1.3E-09 0.500 None 0.971 34 3 1995 2019
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		O00300 TNF receptor superfamily member 11b 443 0.422 0.808 0.16 0.100 None 0.931 29 3 2001 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 0.944 18 3 2000 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.100 None 0.944 18 3 2006 2020
Entrez Id: 5891
Gene Symbol: MOK
MOK 		Q9UQ07 MOK protein kinase Kinase 251 0.476 0.769 8.8E-22 0.030 None 1.000 3 3 2014 2019
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2 		O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 109 0.578 0.692 0.36 0.420 None 1.000 3 3 2014 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.989 174 2 1989 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 0.967 60 2 1992 2020
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5 		Q9UNA0 ADAM metallopeptidase with thrombospondin type 1 motif 5 Enzyme 85 0.597 0.654 8.0E-07 0.100 None 0.962 53 2 2002 2020
Entrez Id: 8200
Gene Symbol: GDF5
GDF5 		P43026 growth differentiation factor 5 Signaling 238 0.511 0.692 0.67 0.400 None 0.960 50 2 2007 2019
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.100 None 0.975 40 2 1996 2019
Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4 		O75173 ADAM metallopeptidase with thrombospondin type 1 motif 4 Enzyme 84 0.582 0.692 2.0E-06 0.100 None 0.971 35 2 2002 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 0.971 34 2 1994 2019
Entrez Id: 6662
Gene Symbol: SOX9
SOX9 		P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.100 None 0.966 29 2 2007 2020
Entrez Id: 2487
Gene Symbol: FRZB
FRZB 		Q92765 frizzled related protein 89 0.573 0.654 1.1E-03 0.400 None 0.923 26 2 1998 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.400 None 1.000 15 2 2002 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.080 None 1.000 8 2 2003 2020