Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		P22607 fibroblast growth factor receptor 3 Kinase 49 0.391 0.846 1.6E-05 0.650 None 1.000 0 1 2013 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.500 None 1.000 0 10 2001 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.500 None 0.987 0 6 1989 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 93 0.380 0.808 1.00 0.440 None 0.833 0 5 2008 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 48 0.418 0.885 0.85 0.430 None 1.000 0 1 2014 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 67 0.390 0.808 0.49 0.420 None 1.000 0 2 2010 2016
Entrez Id: 369
Gene Symbol: ARAF
ARAF 		P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 7 0.619 0.654 0.96 0.410 None 1.000 0 2 2014 2016
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.410 None 1.000 0 1 2008 2018
Entrez Id: 2044
Gene Symbol: EPHA5
EPHA5 		P54756 EPH receptor A5 Kinase 3 0.626 0.615 7.3E-05 0.400 None 1.000 0 2 2005 2005
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1 		Q14145 kelch like ECH associated protein 1 29 0.475 0.808 3.9E-04 0.400 None 1.000 0 0 2015 2020
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 72 0.374 0.885 5.6E-47 0.400 None 0.900 0 3 2009 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.400 None 1.000 0 0 2008 2020
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		Q16539 mitogen-activated protein kinase 14 Kinase 24 0.379 0.923 0.37 0.380 None 1.000 0 0 2011 2019
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 53 0.378 0.885 1.00 0.360 None 1.000 0 0 2001 2019
Entrez Id: 65125
Gene Symbol: WNK1
WNK1 		Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 14 0.416 0.846 1.00 0.340 None 1.000 0 0 2015 2019
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4 		P22455 fibroblast growth factor receptor 4 Kinase 6 0.490 0.769 7.2E-13 0.340 None 1.000 0 0 2005 2013
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B 		P42772 cyclin dependent kinase inhibitor 2B 13 0.417 0.769 7.3E-03 0.330 None 1.000 0 1 2004 2014
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.330 None 1.000 0 0 2011 2015
Entrez Id: 26524
Gene Symbol: LATS2
LATS2 		Q9NRM7 large tumor suppressor kinase 2 Kinase 15 0.554 0.654 0.99 0.330 None 1.000 0 0 2014 2019
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 30 0.456 0.923 3.5E-09 0.320 None 1.000 0 0 2017 2019
Entrez Id: 2042
Gene Symbol: EPHA3
EPHA3 		P29320 EPH receptor A3 Kinase 11 0.497 0.692 1.2E-05 0.320 None 1.000 0 0 2012 2015
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 58 0.479 0.808 1.00 0.320 None 1.000 0 0 2011 2019
Entrez Id: 10188
Gene Symbol: TNK2
TNK2 		Q07912 tyrosine kinase non receptor 2 Kinase 11 0.623 0.538 8.2E-12 0.320 None 1.000 0 0 2014 2017
Entrez Id: 7273
Gene Symbol: TTN
TTN 		Q8WZ42 titin Kinase 41 0.470 0.885 2.6E-96 0.310 None 1.000 0 0 2019 2019
Entrez Id: 2081
Gene Symbol: ERN1
ERN1 		O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 16 0.513 0.808 0.99 0.310 None 1.000 0 1 2017 2017