Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3075
Gene Symbol: CFH
CFH
P08603 complement factor H 393 0.441 0.885 0.86 0.500 None 0.961 486 85 2005 2019
Entrez Id: 59338
Gene Symbol: PLEKHA1
PLEKHA1
Q9HB21 pleckstrin homology domain containing A1 Epigenetic regulator 17 0.769 0.269 2.3E-04 0.200 None 0.867 15 35 2005 2018
Entrez Id: 1589
Gene Symbol: CYP21A2
CYP21A2
P08686 cytochrome P450 family 21 subfamily A member 2 166 0.525 0.769 2.6E-04 0.100 None 1.000 11 29 2010 2018
Entrez Id: 343450
Gene Symbol: KCNT2
KCNT2
Q6UVM3 potassium sodium-activated channel subfamily T member 2 24 0.711 0.308 4.2E-02 0.100 None 1.000 3 29 2013 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 0.971 174 12 2000 2020
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.500 limited 0.940 133 12 2006 2019
Entrez Id: 629
Gene Symbol: CFB
CFB
P00751 complement factor B 139 0.532 0.769 4.7E-16 0.700 limited 0.966 58 12 2006 2019
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.700 limited 1.000 36 12 2007 2020
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
Q92496 complement factor H related 4 11 0.839 0.346 2.4E-18 0.420 moderate 1.000 8 12 2008 2018
Entrez Id: 717
Gene Symbol: C2
C2
P06681 complement C2 71 0.617 0.692 1.3E-16 0.680 limited 1.000 13 9 2006 2018
Entrez Id: 387715
Gene Symbol: ARMS2
ARMS2
P0C7Q2 age-related maculopathy susceptibility 2 36 0.670 0.308 5.2E-04 0.700 limited 0.951 182 8 2005 2019
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
P78363 ATP binding cassette subfamily A member 4 Transporter 227 0.493 0.769 5.3E-48 0.700 strong 0.957 70 7 1997 2019
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 310 0.457 0.885 6.1E-02 0.100 None 0.955 22 7 2004 2019
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
O15315 RAD51 paralog B 126 0.556 0.769 2.1E-15 0.130 None 1.000 5 7 2013 2018
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.200 None 1.000 12 6 2011 2019
Entrez Id: 81494
Gene Symbol: CFHR5
CFHR5
Q9BXR6 complement factor H related 5 43 0.659 0.385 2.1E-32 0.120 None 0.833 6 6 2009 2016
Entrez Id: 102060414
Gene Symbol: C2-AS1
C2-AS1
C2 antisense RNA 1 10 0.821 0.192 0.100 None 1.000 4 6 2010 2012
Entrez Id: 7936
Gene Symbol: NELFE
NELFE
P18615 negative elongation factor complex member E 40 0.686 0.500 6.9E-03 0.120 None 1.000 3 6 2009 2013
Entrez Id: 6499
Gene Symbol: SKIV2L
SKIV2L
Q15477 Ski2 like RNA helicase 96 0.615 0.654 1.3E-22 0.190 None 1.000 15 5 2009 2018
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
P17948 fms related receptor tyrosine kinase 1 Kinase 424 0.419 0.846 1.00 0.070 None 1.000 7 5 2003 2018
Entrez Id: 10516
Gene Symbol: FBLN5
FBLN5
Q9UBX5 fibulin 5 Calcium-binding protein 150 0.546 0.692 1.00 0.370 limited 0.857 7 5 2004 2016
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.060 None 0.833 6 5 2004 2016
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 109 0.578 0.692 0.36 0.100 None 1.000 5 5 2010 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.500 None 0.902 61 4 1998 2019
Entrez Id: 3426
Gene Symbol: CFI
CFI
P05156 complement factor I 133 0.569 0.731 3.5E-08 0.500 None 0.960 25 4 2009 2019