Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 10 0 1995 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2008 2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.010 None 1.000 1 0 1988 1988
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.020 None 1.000 2 0 2000 2018
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.010 None 1.000 1 0 2008 2008
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2004 2004
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 2010 2010
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 2002 2002
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.010 None 1.000 1 0 2010 2010
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.010 None 1.000 1 0 2013 2013
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.300 strong 1.000 1 0 2017 2017
Entrez Id: 947
Gene Symbol: CD34
CD34
P28906 CD34 molecule 674 0.368 0.808 5.0E-06 0.060 None 1.000 6 0 2008 2015
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2009 2009
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.030 None 1.000 3 0 1998 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.010 None 1.000 1 0 1988 1988
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.300 strong 1.000 1 0 2017 2017
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.010 None 1.000 1 0 2004 2004