Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 100128998
Gene Symbol: C20orf181
C20orf181
chromosome 20 open reading frame 181 246 0.479 0.885 0.020 None 0.500 2 0 2018 2018
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Q9Y6K1 DNA methyltransferase 3 alpha 350 0.445 0.846 7.4E-39 0.200 None 1.000 1 0 2013 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.200 None 1.000 1 0 2014 2014
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.200 None 1.000 1 0 2014 2014
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 Transporter 317 0.474 0.846 8.0E-24 0.200 None 1.000 2 0 2013 2014
Entrez Id: 7498
Gene Symbol: XDH
XDH
P47989 xanthine dehydrogenase Enzyme 165 0.529 0.846 2.6E-22 0.300 None 1.000 1 0 2002 2002
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6
P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 257 0.507 0.808 5.2E-22 0.200 None 1.000 1 0 1999 1999
Entrez Id: 5337
Gene Symbol: PLD1
PLD1
Q13393 phospholipase D1 104 0.576 0.731 4.8E-21 0.300 None 1.000 1 0 2002 2002
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.500 None 1.000 2 0 2009 2014
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.200 None 1.000 1 0 2014 2014
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.200 None 1.000 1 0 2011 2011
Entrez Id: 8883
Gene Symbol: NAE1
NAE1
Q13564 NEDD8 activating enzyme E1 subunit 1 Enzyme 18 0.736 0.462 1.8E-13 0.200 None 1.000 1 0 2011 2011
Entrez Id: 2559
Gene Symbol: GABRA6
GABRA6
Q16445 gamma-aminobutyric acid type A receptor subunit alpha6 Ion channel 37 0.678 0.423 1.3E-12 0.300 None 1.000 1 0 2014 2014
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.200 None 1.000 1 0 2007 2007
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
Q9UBU3 ghrelin and obestatin prepropeptide 183 0.517 0.769 1.4E-11 0.200 None 1.000 1 0 2009 2009
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.200 None 1.000 2 0 2011 2014
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 306 0.459 0.885 8.1E-09 0.200 None 1.000 1 0 2012 2012
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.200 None 1.000 1 0 2013 2013
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
P36955 serpin family F member 1 Enzyme modulator 294 0.460 0.846 7.8E-08 0.200 None 1.000 1 0 2012 2012
Entrez Id: 56848
Gene Symbol: SPHK2
SPHK2
Q9NRA0 sphingosine kinase 2 Kinase 140 0.546 0.731 1.3E-07 0.300 None 1.000 1 0 2012 2012
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.200 None 1.000 1 0 2005 2005
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
P19875 C-X-C motif chemokine ligand 2 Signaling 186 0.513 0.885 3.6E-07 0.300 None 1.000 1 0 2002 2002
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.200 None 1.000 2 0 2013 2013