Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 1.000 12 3 1993 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.010 None 1.000 1 2 2011 2011
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.700 strong 0.973 37 1 1995 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 14 1 1999 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.340 None 1.000 5 1 1987 2012
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 304 0.457 0.769 2.2E-05 0.030 None 1.000 3 1 2004 2014
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.030 None 1.000 3 1 2017 2020
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.020 None 1.000 2 1 2012 2013
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.020 None 0.500 2 1 2007 2016
Entrez Id: 3603
Gene Symbol: IL16
IL16
Q14005 interleukin 16 Signaling 193 0.501 0.846 1.2E-10 0.020 None 1.000 2 1 2015 2016
Entrez Id: 407041
Gene Symbol: MIR34B
MIR34B
microRNA 34b 165 0.509 0.808 0.010 None 1.000 1 1 2014 2014
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.010 None 1.000 1 1 2013 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.300 None 0 1
Entrez Id: 2271
Gene Symbol: FH
FH
P07954 fumarate hydratase Enzyme 231 0.489 0.846 8.8E-02 0.600 strong 0.971 34 0 2002 2020
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.400 None 1.000 17 0 1990 2019
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
Q8NFG4 folliculin 160 0.537 0.885 0.79 0.600 strong 1.000 15 0 2002 2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.100 None 1.000 12 0 2012 2020
Entrez Id: 7030
Gene Symbol: TFE3
TFE3
P19532 transcription factor binding to IGHM enhancer 3 118 0.542 0.654 0.98 0.100 None 1.000 12 0 2007 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.400 strong 1.000 11 0 1998 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 1.000 11 0 2014 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.090 None 1.000 9 0 1988 2019
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.390 strong 1.000 9 0 1997 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.080 None 1.000 8 0 2004 2019
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
Q99814 endothelial PAS domain protein 1 Transcription factor 293 0.454 0.731 0.60 0.080 None 1.000 8 0 2011 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.560 None 0.857 7 0 2013 2019