Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.310 None 0.500 1 0 2011 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.330 None 1.000 2 0 2004 2017
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 75 0.336 0.885 0.48 0.310 None 1.000 1 0 1984 1990
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.300 None 1.000 2 0 2011 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		P10451 secreted phosphoprotein 1 81 0.353 0.885 2.1E-06 0.300 None 1.000 1 0 2006 2006
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 89 0.378 0.885 8.7E-02 0.300 None 1.000 1 0 2012 2012
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.310 None 1.000 1 0 1988 2017
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.300 None 1.000 1 0 2011 2011
Entrez Id: 5111
Gene Symbol: PCNA
PCNA 		P12004 proliferating cell nuclear antigen Nucleic acid binding 26 0.382 0.846 0.98 0.300 None 1.000 1 0 2011 2011
Entrez Id: 6285
Gene Symbol: S100B
S100B 		P04271 S100 calcium binding protein B Calcium-binding protein 44 0.383 0.923 4.4E-02 0.300 None 1.000 1 0 2017 2017
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 45 0.396 0.846 3.2E-06 0.320 None 1.000 1 0 2012 2019
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 46 0.398 0.885 1.00 0.300 None 1.000 1 0 1998 1998
Entrez Id: 6657
Gene Symbol: SOX2
SOX2 		P48431 SRY-box transcription factor 2 Transcription factor 40 0.405 0.808 0.71 0.300 None 1.000 1 0 2017 2017
Entrez Id: 5970
Gene Symbol: RELA
RELA 		Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 63 0.406 0.885 1.00 0.300 None 1.000 1 0 2011 2011
Entrez Id: 5444
Gene Symbol: PON1
PON1 		P27169 paraoxonase 1 112 0.409 0.885 9.8E-11 0.300 None 1.000 1 0 2005 2005
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 37 0.412 0.808 6.3E-02 0.310 None 1.000 1 0 2011 2017
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		P16455 O-6-methylguanine-DNA methyltransferase 26 0.412 0.885 1.2E-07 0.300 None 1.000 1 0 2010 2010
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 71 0.413 0.846 0.13 0.300 None 1.000 1 0 2017 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		P46937 Yes associated protein 1 Enzyme modulator 31 0.432 0.808 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2 		P05107 integrin subunit beta 2 Receptor 27 0.444 0.923 5.1E-15 0.300 None 1.000 1 0 2017 2017
Entrez Id: 7052
Gene Symbol: TGM2
TGM2 		P21980 transglutaminase 2 Enzyme 32 0.445 0.808 6.8E-18 0.300 None 1.000 1 0 2005 2005
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1 		P53355 death associated protein kinase 1 Kinase 43 0.472 0.808 1.00 0.300 None 1.000 1 0 2007 2007
Entrez Id: 6608
Gene Symbol: SMO
SMO 		Q99835 smoothened, frizzled class receptor G-protein coupled receptor 59 0.489 0.731 4.3E-07 0.300 None 1.000 1 0 1998 1998
Entrez Id: 28514
Gene Symbol: DLL1
DLL1 		O00548 delta like canonical Notch ligand 1 23 0.492 0.808 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9 		P11712 cytochrome P450 family 2 subfamily C member 9 31 0.506 0.885 1.3E-10 0.310 None 1.000 1 0 2006 2016