Gene: EGFR ×
Source: BEFREE ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE <i>EGFR</i> mutation is highly related to female, nonsmoking and adenocarcinoma. 30210620 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE - Recurrent epidermal growth factor receptor ( EGFR) mutations are seen in a subset of pulmonary adenocarcinomas. 29106293 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinoma with epidermal growth factor receptor gene mutations in three siblings. 18317075 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 Biomarker group BEFREE Adenocarcinomas revealed 399 days to progression (TTP) and 548 days overall survival (OS) for EGFR mutated vs. 119 days to progression and 137 days survival for non-mutated, p<0.0001 (TTP) and p=0.0001 (OS). 19596959 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinoma in patients with mutant EGFR and non-smoker status in patients with wild-type EGFR were associated with better overall survival after TK inhibitor treatment. 20832137 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinoma is the most frequent EGFR mutation pathologic type in lung cancer. 21933587 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinomas, the most common histologic subtype of non-small cell lung cancer (NSCLC), are frequently associated with activating mutations in the epidermal growth factor receptor (EGFR) gene. 22738915 2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinoma (ADC) of the lung may harbor EGFR- or KRAS-mutations, which are relevant for treatment decisions. 25982011 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinomas harboring EGFR exon 21 mutation were less malignant than adenocarcinomas harboring exon 19 mutation. 27272827 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinoma with lepidic pattern is a low-grade lung tumor with favorable prognosis and displays frequent EGFR mutation. 27738759 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinoma with epidermal growth factor receptor (EGFR) mutations accounts for 8%-30% of all cases of NSCLC depending on the geography and ethnicity. 28367058 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Adenocarcinomas with EGFR mutations had a higher GGO proportion than those with wild-type EGFR after matching of clinical variables. 30089595 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 AlteredExpression group BEFREE Epidermal growth factor receptor overexpression is pronounced in virtually all squamous carcinomas and is also found in > or = 65% of large cell and adenocarcinomas. 11894009 2002
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 AlteredExpression group BEFREE EGFR protein is overexpressed in a significant percentage of colonic adenocarcinomas. 12884235 2003
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR mutations were frequently associated with adenocarcinoma (P < 0.0001), never smoker (P < 0.0001), and female gender (P = 0.0001). 15709185 2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE Epidermal growth factor receptor mutations may play a key role in the development of smoking-independent adenocarcinoma. 16052218 2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 AlteredExpression group BEFREE EGFR and HER2 proteins were expressed in 23 and 17 of 55 adenocarcinomas with MX. 16189154 2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR mutations correlated with previously identified clinical features of gefitinib response, including adenocarcinoma histology, absence of smoking history, female sex, and Asian ethnicity. 16204011 2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR mutations were prevalent in adenocarcinomas (115 of 215), uncommon in LELC (1 of 11), and not found in SCC (P < 0.001). 16533793 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR mutations were found in 136 cases (42.2%) with adenocarcinoma, in one case with large cell carcinoma, and in one case with pleomorphic carcinoma. 16552419 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 AlteredExpression group BEFREE EGFR protein expression was more common in squamous cell carcinoma (SCC; 17 [26.2%]) than in adenocarcinoma (14 [11.1%]; (P = .0076) and more frequently associated with EGFR amplification (8 [14.5%] vs 4 [3.6%] cases; P = .0208). 16690485 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR mutations are more frequent in Asians, females, nonsmokers, and adenocarcinomas than in their counterparts. 16850125 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR protein expression and gene mutations in exons 18, 19 and 21 were investigated in 49 gastric adenocarcinomas. 17094480 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 GeneticVariation group BEFREE EGFR mutations were associated with adenocarcinoma (p = 0.002), female gender (p = 0.02), never-smoking (p < 0.0001), Asian ethnicity (p = 0.005), air bronchograms (p = 0.004), and multiple wedge resections (p = 0.03). 17409862 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 AlteredExpression group BEFREE EGFR TKD mutations were detected in 25 of 48 adenocarcinomas (52.1%), and overexpression of EGFR protein was identified in 19 patients (39.6%). 17409961 2006