Gene: MIR21 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.060 Biomarker group BEFREE It has been reported that microRNA-21 (miR-21) augments Th17 responses and contributes to the pathogenesis of autoimmune diseases. 30502648 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.060 Biomarker group BEFREE Therefore, we demonstrate that miR-21-5p can serve as a therapeutic target in the management of uveitis and other autoimmune diseases. 31228813 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.060 Biomarker group BEFREE Thus, we characterized a B cell-intrinsic microRNA pathway that inhibits the differentiation of IL-10<sup>+</sup> Breg cells and promotes autoimmunity. miR-21 silencing therefore represents a new therapeutic strategy for the treatment of autoimmune diseases. 29212210 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.060 Biomarker group BEFREE The aim of the present study was to assess the mechanism of miR-21 in autoimmune disease, particularly, the autoimmune lymphoid hyperplasia syndrome. 28588726 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.060 Biomarker group BEFREE Collectively, our experiments demonstrate that miR-21 deficiency in cGVHD host mice is sufficient to protect from lupus-like autoimmunity. 26631756 2016
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.060 Biomarker group BEFREE We also discussed the therapeutic potential of targeting miR-21 in treating patients with autoimmune disease. 27271606 2016