Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 AlteredExpression disease BEFREE The purpose of this study was to investigate immunohistochemicaly the influence of MMP-1, MMP-3, MMP-9 and MMP-13 expression on prognostic parameter in chondrosarcoma. 29316907 2018
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 AlteredExpression disease BEFREE We previously reported that human MMP3 could translocate into cellular nuclei and control transcription in human chondrosarcoma-derived cells and in articular cartilage (Eguchi et al. 27206651 2017
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 AlteredExpression disease BEFREE The present study aimed to investigate the effects of Icariin on matrix metalloproteinase (MMP)‑1, MMP‑3 and MMP‑13 expression in interleukin (IL)‑1β‑stimulated human SW1353 chondrosarcoma cells, and to investigate the possible mechanism underlying the chondroprotective effects of Icariin. 28447732 2017
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 AlteredExpression disease BEFREE In the current study, we report that roxatidine attenuated TNF-α- induced degradation of type II collagen by suppressing the expression of MMP-3 and MMP-13 in human chondrosarcoma cell line SW1353 cells. 28926925 2017
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 Biomarker disease BEFREE Stable knock-down of CSPG4/NG2 in the JJ012 chondrosarcoma cell line by shRNA resulted in decreased cell proliferation and migration as well as a decrease in gene expression of the MMP (matrix metalloproteinase) 3 protease and ADAMTS4 (aggrecanase). 27292772 2016
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 AlteredExpression disease BEFREE The requirements of NF-kappaB translocation and p38 activity are indispensably involved in the induction of MMP-3 expression in chondrosarcoma cells stimulated by IL-1beta. 18340449 2008
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 Biomarker disease LHGDN SW1353 cells, a human chondrosarcoma cell line, were stimulated with interleukin (IL) 1alpha and tumor necrosis factor (TNF) alpha, and the concentrations of activin A, follistatin, and MMP-3 secreted into the culture media were measured by enzyme-linked immunosorbent assay (ELISA). 17436000 2007