Gene: IGHV3-21 ×
Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 28444
Gene Symbol: IGHV3-21
IGHV3-21 		0.600 Biomarker disease ORPHANET Clinically, co-occurrence of SF3B1 mutations and subset 2 BCR configuration prompts disease progression in IGHV3-21-CLL, whereas cooperation between NOTCH1 mutations, +12, and subset 8 BCR configuration invariably primes CLL transformation into Richter syndrome. 23637131 2013
Entrez Id: 28444
Gene Symbol: IGHV3-21
IGHV3-21 		0.600 Biomarker disease ORPHANET To investigate the IGHV3-21 frequency and the clinical impact of IGHV3-21 stereotypy, 337 newly diagnosed Swedish CLL patients from a population-based cohort were analyzed. 22464020 2012
Entrez Id: 28444
Gene Symbol: IGHV3-21
IGHV3-21 		0.600 Biomarker disease ORPHANET T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients. 22875913 2012
Entrez Id: 28444
Gene Symbol: IGHV3-21
IGHV3-21 		0.600 Biomarker disease ORPHANET IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells. 21372840 2011
Entrez Id: 28444
Gene Symbol: IGHV3-21
IGHV3-21 		0.600 Biomarker disease CTD_human Distinctive gene expression pattern in VH3-21 utilizing B-cell chronic lymphocytic leukemia. 15817677 2005