Gene: SMAD3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.030 AlteredExpression disease BEFREE TAM or rBMP7 administration significantly inhibited peritoneal Smad3 expression in uremic rats with PF, prevented Smad3 phosphorylation, and induced a remarkable up-regulation of Smad7, an intracellular inhibitor of TGFβ/Smad signaling, contributing to a negative modulation of profibrotic genes. 31455237 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.030 AlteredExpression disease BEFREE The upregulation of profibrotic factors (TGF-β, fibronectin, and Smad3) in the PF group was significantly ameliorated by VPA. 28873458 2017
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.030 Biomarker disease BEFREE The role of Smad3 in the development of dermal fibrosis, subcapsular cataract, and peritoneal fibrosis has been reported. 22139024 2012