Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
0.030 AlteredExpression disease BEFREE In contrast, a significant, positive correlation between SFRP1 level and IOP was detected in the AACG group. 31382918 2019
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
0.030 Biomarker disease BEFREE Elevated SFRP1 increased IOP in mice eyes and in perfusion cultured anterior segments of the human eye. 22248913 2012
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
0.030 AlteredExpression disease BEFREE Thus, these data indicate that increased expression of sFRP1 in the TM appears to be responsible for elevated IOP in glaucoma and restoring Wnt signaling in the TM may be a novel disease intervention strategy for treating glaucoma. 18274669 2008