Gene: MYH7 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Characterization of mutant myosins of Dictyostelium discoideum equivalent to human familial hypertrophic cardiomyopathy mutants. Molecular force level of mutant myosins may have a prognostic implication. 9062359 1997
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR A DNA resequencing array for pathogenic mutation detection in hypertrophic cardiomyopathy. 18409188 2008
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR [Biochemical characterization of a high-molecular weight alkaline phosphatase in a patient with cholangiocarcinoma (alpha-1 alkaline phosphatase)]. 2411171 1985
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Usefulness of Genetic Testing in Hypertrophic Cardiomyopathy: an Analysis Using Real-World Data. 28138913 2017
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Penetrance of hypertrophic cardiomyopathy in children and adolescents: a 12-year follow-up study of clinical screening and predictive genetic testing. 23197161 2013
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR "Hypertrophic cardiomyopathy: two homozygous cases with ""typical"" hypertrophic cardiomyopathy and three new mutations in cases with progression to dilated cardiomyopathy." 12951062 2003
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations. 24829265 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy. 11106718 2000
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy. 9172070 1997
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Development of a high resolution melting method for the detection of genetic variations in hypertrophic cardiomyopathy. 20800588 2010
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Missense mutations in the beta-myosin heavy-chain gene cause central core disease in hypertrophic cardiomyopathy. 8483915 1993
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Array-based resequencing assay for mutations causing hypertrophic cardiomyopathy. 18258667 2008
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Detection of a large duplication mutation in the myosin-binding protein C3 gene in a case of hypertrophic cardiomyopathy. 23816408 2013
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Identification of a novel TPM1 mutation in a family with left ventricular noncompaction and sudden death. 20965760 2011
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Genetic testing impacts the utility of prospective familial screening in hypertrophic cardiomyopathy through identification of a nonfamilial subgroup. 28640247 2018
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. 16352453 2006
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2. 17192269 2007
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Molecular etiology of idiopathic cardiomyopathy in Asian populations. 11433818 2001
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Disease penetrance and risk stratification for sudden cardiac death in asymptomatic hypertrophic cardiomyopathy mutation carriers. 19666645 2009
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function. 16983074 2006
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR A p.R870H mutation in the beta-cardiac myosin heavy chain 7 gene causes familial hypertrophic cardiomyopathy in several members of an Indian family. 17703256 2007
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy. 24865491 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Spectrum and clinical manifestations of mutations in genes responsible for hypertrophic cardiomyopathy. 22455086 2012
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Resequencing the whole MYH7 gene (including the intronic, promoter, and 3' UTR sequences) in hypertrophic cardiomyopathy. 22765922 2012
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Genetic testing for dilated cardiomyopathy in clinical practice. 22464770 2012