Gene: MYH7 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. 25611685 2015
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians. 25448463 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Genetics of hypertrophic cardiomyopathy in Norway. 24111713 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations. 24835277 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations. 24829265 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy. 24865491 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Nationwide study on hypertrophic cardiomyopathy in Iceland: evidence of a MYBPC3 founder mutation. 25078086 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Novel mutations widen the phenotypic spectrum of slow skeletal/β-cardiac myosin (MYH7) distal myopathy. 24664454 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise. 24510615 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Abnormal cardiac formation in hypertrophic cardiomyopathy: fractal analysis of trabeculae and preclinical gene expression. 24704860 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Characterization of a phenotype-based genetic test prediction score for unrelated patients with hypertrophic cardiomyopathy. 24793961 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Familial hypertrophic cardiomyopathy: functional variance among individual cardiomyocytes as a trigger of FHC-phenotype development. 25346696 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR The landscape of genetic variation in dilated cardiomyopathy as surveyed by clinical DNA sequencing. 24503780 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Malignant effects of multiple rare variants in sarcomere genes on the prognosis of patients with hypertrophic cardiomyopathy. 25132132 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR A new common mutation in the cardiac beta-myosin heavy chain gene in Finnish patients with hypertrophic cardiomyopathy. 24888384 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations. 25524337 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Characterization of a phenotype-based genetic test prediction score for unrelated patients with hypertrophic cardiomyopathy. 24793961 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Sarcomere mutation-specific expression patterns in human hypertrophic cardiomyopathy. 25031304 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR Genetics of hypertrophic cardiomyopathy in Norway. 24111713 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Malignant effects of multiple rare variants in sarcomere genes on the prognosis of patients with hypertrophic cardiomyopathy. 25132132 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease BEFREE Exome sequencing identifies a novel MYH7 p.G407C mutation responsible for familial hypertrophic cardiomyopathy. 24963656 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease BEFREE Whole exome sequencing analysis revealed a R249Q-MYH7 mutation associated previously with familial hypertrophic cardiomyopathy, sudden death, and impaired β-myosin heavy chain (MHC-β) actin-translocating and actin-activated ATPase (adenosine triphosphatase) activity. 24298987 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 CausalMutation disease CLINVAR The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin. 24344137 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease CLINVAR Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise. 24510615 2014
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.500 GeneticVariation disease BEFREE To investigate the molecular mechanism underlying the abnormal CM functions in HCM, we derived iPSCs from an HCM patient with a single missense mutation (Arginine442Glycine) in the MYH7 gene. 25209314 2014