Gene: EGFR ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE EGFR mutations were detected by both DHPLC procedure and direct sequencing using lung cancer tissue samples obtained from 97 patients (81 surgical specimens and 16 pleural effusions of non-resectable lung cancer patients). 16947044 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE Epidermal growth factor receptor mutation in lung cancer are linked to bronchioloalveolar differentiation. 17001163 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer. 17052295 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE Epidermal growth factor receptor mutations in lung cancer. 17318210 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy. 17353898 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 AlteredExpression disease BEFREE EGFR expression as an ancillary tool for diagnosing lung cancer in cytology specimens. 17643093 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE EGFR insertion mutations at exon 20 were found from 7 of 322 (2.17%) lung cancer patients. 17686547 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR tyrosine kinase inhibitors in lung cancer: an evolving story. 17716025 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines. 18304967 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids. 18372921 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE Epidermal growth factor receptor gene amplification is acquired in association with tumor progression of EGFR-mutated lung cancer. 18381415 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE Epidermal growth factor receptor (EGFR) mutations in lung cancer enhance tyrosine kinase activity and increase sensitivity to the EGFR tyrosine kinase inhibitor, gefitinib. 18422739 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE EGFR polymorphism of the kinase domain in Japanese lung cancer. 18541260 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR assays in lung cancer. 18580100 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer. 19058870 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR-targeted therapies in lung cancer: predictors of response and toxicity. 19102716 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR may be a promising therapeutic molecular target for lung cancer treatment using verapamil and/or chemotherapeutic agents. 19331130 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 AlteredExpression disease BEFREE EGFR mRNA was detected in 83.3% (25/30) and 70% (7/10) of brain metastasis from lung cancer and breast cancer, respectively. 19402080 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE Epidermal growth factor receptor-regulated miR-125a-5p--a metastatic inhibitor of lung cancer. 19702827 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR amplification was focally distributed in lung cancer specimens, mostly in regions with solid histology. 19826035 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE Epidermal growth factor receptor (EGFR) is overexpressed in a variety of epithelial malignancies including lung cancer in which EGFR aberrations not only predict response to EGFR tyrosine kinase inhibitors but also indicate tumor progression. 20347505 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE EGFR-expressing lung cancer cell lines were able to bind cetuximab and initiate complement activation by the classical pathway, irrespective of the mutational status of EGFR. 20529262 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE Epidermal growth factor receptor (EGFR) signaling pathway plays a crucial role in the development and progression of lung cancer. 20881644 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease BEFREE EGFR mutations and lung cancer. 20887192 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE Epidermal growth factor receptor (EGFR) and MET are molecular targets for lung cancer treatment. 20934974 2010