STE can relieve the PAH in rats.STE may relieve pulmonary vascular disease and pulmonary injury by down-regulating the expression of NF-κB p65 and α-SMA.
Western blotting demonstrated that the protein expression levels of p-IκB, p-P65, and P65 in rat pulmonary tissues of PAH group were remarkably higher than CTL group (p<0.01).