DisGeNET - a database of gene-disease associations

Hereditary Nonpolyposis Colorectal Cancer, C1333990

N. genes: 6; N. variants: 1268

Source: CLINVAR ×

Results per page

Gene

Disease 2

Variant

Source

Semantic type

Disease Class

Type

HPO Term

DO Class

N. genes1

N. genes2

N. of shared genes

Jaccard_g

p-value_g

N. variants1

N. variants2

N. of shared variants

Jaccard_v

p-value_v

Associated Disease

N. genes

N. variants

N. of shared genes

JI_g

p-value_g

N. of shared variants

JI_v

p-value_v

CUI:	C0005684
Disease:	Malignant neoplasm of urinary bladder

Malignant neoplasm of urinary bladder

7

17

1

8.3E-02

1

7.8E-04

CUI:	C0006413
Disease:	Burkitt Lymphoma

Burkitt Lymphoma

1

2

1

0.17

2

1.6E-03

CUI:	C0009376
Disease:	Colonic Polyps

2

2

1

0.14

1

7.9E-04

CUI:	C0020459
Disease:	Hyperinsulinism

Hyperinsulinism

4

0

1

0.11

0

0

CUI:	C0022665
Disease:	Kidney Neoplasm

Kidney Neoplasm

6

6

1

9.1E-02

1

7.9E-04

CUI:	C0023418
Disease:	leukemia

2

2

1

0.14

1

7.9E-04

CUI:	C0023449
Disease:	Acute lymphocytic leukemia

Acute lymphocytic leukemia

5

12

1

1.0E-01

1

7.8E-04

CUI:	C0024299
Disease:	Lymphoma

6

10

1

9.1E-02

3

2.4E-03

CUI:	C0034088
Disease:	Pulmonary Valve Insufficiency

Pulmonary Valve Insufficiency

2

2

1

0.14

1

7.9E-04

CUI:	C0034885
Disease:	Rectal Neoplasms

Rectal Neoplasms

1

0

1

0.17

0

0

CUI:	C0035229
Disease:	Respiratory Insufficiency

Respiratory Insufficiency

11

15

1

6.2E-02

1

7.8E-04

CUI:	C0037286
Disease:	Skin Neoplasms

2

2

1

0.14

1

7.9E-04

CUI:	C0153436
Disease:	Malignant neoplasm of sigmoid colon

Malignant neoplasm of sigmoid colon

1

1

1

0.17

1

7.9E-04

CUI:	C0153439
Disease:	Malignant neoplasm of ascending colon

Malignant neoplasm of ascending colon

1

1

1

0.17

1

7.9E-04

CUI:	C0153567
Disease:	Uterine Cancer

1

1

1

0.17

1

7.9E-04

CUI:	C0241240
Disease:	Tall stature

11

0

1

6.2E-02

0

0

CUI:	C0346300
Disease:	Pituitary carcinoma

Pituitary carcinoma

1

1

1

0.17

1

7.9E-04

CUI:	C0677776
Disease:	Hereditary Breast and Ovarian Cancer Syndrome

Hereditary Breast and Ovarian Cancer Syndrome

17

0

1

4.5E-02

0

0

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

15

37

1

5.0E-02

1

7.7E-04

CUI:	C1140680
Disease:	Malignant neoplasm of ovary

Malignant neoplasm of ovary

11

20

1

6.2E-02

1

7.8E-04

CUI:	C1319315
Disease:	Adenocarcinoma of large intestine

Adenocarcinoma of large intestine

9

11

1

7.1E-02

1

7.8E-04

CUI:	C1707251
Disease:	Cancer Other

2

2

1

0.14

1

7.9E-04

CUI:	C1838333
Disease:	COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4

COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4

2

39

1

0.14

22

1.7E-02

CUI:	C1843367
Disease:	Poor school performance

Poor school performance

211

0

1

4.6E-03

0

0

CUI:	C1849265
Disease:	Overgrowth

81

0

1

1.2E-02

0

0