Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
RELN P78509 reelin 1.00 0.515 0.731
IL2 P60568 interleukin 2 0.48 0.336 0.885
TDO2 P48775 tryptophan 2,3-dioxygenase Enzyme 2.0E-10 0.599 0.654
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
LEP P41159 leptin 0.46 0.349 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769