Disease: Depressive disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
RELN P78509 reelin 1.00 0.515 0.731
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
PDE4A P27815 phosphodiesterase 4A 0.98 0.523 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808
GLO1 Q04760 glyoxalase I 9.7E-07 0.537 0.769
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
NPAS2 Q99743 neuronal PAS domain protein 2 1.00 0.595 0.654
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
GABRA3 P34903 gamma-aminobutyric acid type A receptor subunit alpha3 Ion channel 3.9E-02 0.636 0.577
DIXDC1 Q155Q3 DIX domain containing 1 Signaling 7.3E-11 0.647 0.385
ASMT P46597 acetylserotonin O-methyltransferase 1.3E-20 0.691 0.346