Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808
ADRA1A P35348 adrenoceptor alpha 1A G-protein coupled receptor 3.4E-07 0.462 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
BCL9 O00512 BCL9 transcription coactivator 0.50 0.595 0.615
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CDH7 Q9ULB5 cadherin 7 0.60 0.769 0.231
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CAMK2A Q9UQM7 calcium/calmodulin dependent protein kinase II alpha Kinase 1.00 0.612 0.538
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CCKAR P32238 cholecystokinin A receptor G-protein coupled receptor 4.0E-03 0.615 0.500
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769