Disease: Tonic - clonic seizures
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
GRIK1 P39086 glutamate ionotropic receptor kainate type subunit 1 Ion channel 1.2E-09 0.641 0.462
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
MLC1 Q15049 modulator of VRAC current 1 Ion channel 3.2E-08 0.585 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
SLC1A1 P43005 solute carrier family 1 member 1 Transporter 8.7E-06 0.561 0.654
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
IMPA1 P29218 inositol monophosphatase 1 Enzyme 4.8E-04 0.623 0.731
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
SLC6A2 P23975 solute carrier family 6 member 2 Transporter 8.2E-02 0.490 0.846
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
INS P01308 insulin 0.30 0.445 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
SST P61278 somatostatin Signaling 0.34 0.399 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
ADCYAP1 P18509 adenylate cyclase activating polypeptide 1 Signaling 0.52 0.510 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923