Disease: Seizures
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808
ADCYAP1 P18509 adenylate cyclase activating polypeptide 1 Signaling 0.52 0.510 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ATP1A1 P05023 ATPase Na+/K+ transporting subunit alpha 1 Transporter 1.00 0.601 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
CACNA1B Q00975 calcium voltage-gated channel subunit alpha1 B Ion channel 1.00 0.650 0.577
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CUX2 O14529 cut like homeobox 2 Transcription factor 1.00 0.644 0.500
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
GABRA5 P31644 gamma-aminobutyric acid type A receptor subunit alpha5 Ion channel 0.91 0.621 0.385
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRIK1 P39086 glutamate ionotropic receptor kainate type subunit 1 Ion channel 1.2E-09 0.641 0.462