Disease: Depressive disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADCY8 P40145 adenylate cyclase 8 1.8E-06 0.705 0.577
ADCYAP1 P18509 adenylate cyclase activating polypeptide 1 Signaling 0.52 0.510 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 Enzyme 6.8E-30 0.729 0.577
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
ARRB2 P32121 arrestin beta 2 Enzyme modulator 0.51 0.561 0.769
ASMT P46597 acetylserotonin O-methyltransferase 1.3E-20 0.691 0.346
ATF4 P18848 activating transcription factor 4 1.6E-02 0.507 0.769
ATP1A3 P13637 ATPase Na+/K+ transporting subunit alpha 3 Transporter 1.00 0.544 0.615
BAG1 Q99933 BAG cochaperone 1 6.5E-06 0.538 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CALM2 P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 0.92 0.472 0.808
CAMK2A Q9UQM7 calcium/calmodulin dependent protein kinase II alpha Kinase 1.00 0.612 0.538
CHRM2 P08172 cholinergic receptor muscarinic 2 G-protein coupled receptor 0.18 0.585 0.615
CHRNA2 Q15822 cholinergic receptor nicotinic alpha 2 subunit Ion channel 6.5E-10 0.705 0.385
CHRNA6 Q15825 cholinergic receptor nicotinic alpha 6 subunit Ion channel 3.6E-08 0.711 0.346
CHRNB3 Q05901 cholinergic receptor nicotinic beta 3 subunit Ion channel 8.6E-06 0.705 0.308
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808