Disease: MAJOR AFFECTIVE DISORDER 6
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ANK3 Q12955 ankyrin 3 1.00 0.578 0.654
ATP1A3 P13637 ATPase Na+/K+ transporting subunit alpha 3 Transporter 1.00 0.544 0.615
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD5 P21918 dopamine receptor D5 G-protein coupled receptor 1.3E-16 0.603 0.423
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
TACR1 P25103 tachykinin receptor 1 G-protein coupled receptor 3.8E-04 0.502 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
TRPM2 O94759 transient receptor potential cation channel subfamily M member 2 Ion channel 9.0E-44 0.546 0.731