Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
NXN Q6DKJ4 nucleoredoxin 1.00 0.584 0.577
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
HERC2 O95714 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.00 0.568 0.692