| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
| AURKA | O14965 | aurora kinase A | Kinase | 0.87 | 0.475 | 0.731 |
| AXIN2 | Q9Y2T1 | axin 2 | 0.57 | 0.507 | 0.692 | |
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| DCC | P43146 | DCC netrin 1 receptor | 0.99 | 0.471 | 0.808 | |
| DLC1 | Q96QB1 | DLC1 Rho GTPase activating protein | 1.00 | 0.529 | 0.731 | |
| EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
| EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
| FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
| FLCN | Q8NFG4 | folliculin | 0.79 | 0.537 | 0.885 | |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
| MLH3 | Q9UHC1 | mutL homolog 3 | Nucleic acid binding | 4.9E-08 | 0.582 | 0.538 |
| MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
| NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| POLE | Q07864 | DNA polymerase epsilon, catalytic subunit | 8.0E-27 | 0.526 | 0.731 | |
| PRKCB | P05771 | protein kinase C beta | Kinase | 1.00 | 0.453 | 0.885 |
| RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
| RNF43 | Q68DV7 | ring finger protein 43 | 0.73 | 0.584 | 0.577 | |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |