Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
CDH1 P12830 cadherin 1 0.15 0.401 0.808
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
XRCC4 Q13426 X-ray repair cross complementing 4 8.3E-07 0.528 0.769
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
FAN1 Q9Y2M0 FANCD2 and FANCI associated nuclease 1 1.7E-25 0.610 0.577
PTPRJ Q12913 protein tyrosine phosphatase receptor type J Enzyme 1.3E-11 0.606 0.615
RPS20 P60866 ribosomal protein S20 Nucleic acid binding 2.1E-02 0.610 0.692