Disease: Serum LDL cholesterol measurement
Source: GWASDB ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769
CELSR2 Q9HCU4 cadherin EGF LAG seven-pass G-type receptor 2 G-protein coupled receptor 1.00 0.656 0.577
CERT1 Q9Y5P4 ceramide transporter 1 Transporter 0.67 0.674 0.500
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CR1L Q2VPA4 complement C3b/C4b receptor 1 like 7.6E-27 0.931 0.115
DNAH11 Q96DT5 dynein axonemal heavy chain 11 Enzyme 2.5E-58 0.587 0.692
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
HNF1A-AS1 HNF1A antisense RNA 1 0.621 0.538
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MTHFD1L Q6UB35 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Enzyme 1.9E-12 0.674 0.538