Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885